MajorMajor, thanks for posting. The phase two trial study form states "There are no restrictions on breed of dog for the phase 2 study. Dogs must be at least 6 years old, 40 pounds in weight minimum and in good health, without significant pre-existing conditions"
Based on laboratory studies, we anticipate that this regimen of rapamycin treatment could improve healthy longevity of typical pet dogs by 2-5 years. Whether there are in fact dogs with heart issues, actually on the trial I do not know.
The article below also states dogs have to be healthy and over 40 pounds.http://edition.cnn.com/2016/10/06/health/rapamycin-dog-live-longer/index.html